New Meroterpenoids from the Endophytic Fungus Aspergillus flavipes AIL8 Derived from the Mangrove Plant Acanthus ilicifolius

نویسندگان

  • Zhi-Qiang Bai
  • Xiuping Lin
  • Junfeng Wang
  • Xuefeng Zhou
  • Juan Liu
  • Bin Yang
  • Xianwen Yang
  • Shengrong Liao
  • Lishu Wang
  • Yonghong Liu
چکیده

Four new meroterpenoids (2-5), along with three known analogues (1, 6, and 7) were isolated from mangrove plant Acanthus ilicifolius derived endophytic fungus Aspergillus flavipes. The structures of these compounds were elucidated by NMR and MS analysis, the configurations were assigned by CD data, and the stereochemistry of 1 was confirmed by X-ray crystallography analysis. A possible biogenetic pathway of compounds 1-7 was also proposed. All compounds were evaluated for antibacterial and cytotoxic activities.

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عنوان ژورنال:

دوره 13  شماره 

صفحات  -

تاریخ انتشار 2015